{{tag>beta}} ====== Beta Helix ======= In this mainly beta fold, the polypeptide chain is wound into a large right-handed coil (or super helix). There are two different types of beta helix, one with two [[glossary:beta_sheet | beta sheets]], and one with three beta sheets. In our classification scheme we describe these as 2-solenoid and 3-solenoid beta [[glossary:architecture | architectures]], respectively. __2-solenoid__ This architecture comprises of two flat beta sheets packed tightly against one another. It has a highly distinctive and repetitive [[glossary:beta_strand | strand]] connectivity, which distinguishes it from the two layer sandwich architecture. The chain continually alternates between the two sheet layers whilst progressing in a spiraling motion from one end of the structure to the other, hence the term 'solenoid.' This could also be classified as a 2-layer beta sandwich but its unusual lack of curvature and its unusual topology have led to it being identified separately. __3-solenoid__ Structures with this architecture comprise three beta sheets which have a distinctive strand connectivity. The chain visits each sheet in turn and is progressively wound around the principal axis in the same direction. ===== References ===== {{pubmed>long:8081735}} {{pubmed>long:8081738}}