{{tag>alpha}}
====== EF Hand =======

This is a helix-loop-helix, calcium-binding  [[glossary:motif | motif]], in which two [[glossary:alpha_helix | helices]] pack
together at an angle of approximately 90 degrees, separated by a loop region, where
calcium binds. The 'EF' notation for the motif resulted from the structure of parvalbumin, in which the 'E' and 'F' helices were originally identified to form this calcium-binding motif.
The example shown is a human psoriasin (PDB code 1psr).

{{cath:feature>1psrA00}}

===== References =====

{{pubmed>long:8848832}}
{{pubmed>long:4700463}}
{{pubmed>long:2191555}}