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CATH Data

This page provides links to CATH data files from each externally available release of the CATH database.

Alternatively, you can browse all the release files here:

http://release.cathdb.info

You can also look at the release notes for more information on what happened in each release.

Page Notes

  • 08-09-2008 Added links to the descriptions of file formats
  • 03-09-2008 Added links to the HMM libraries and CATH Domain PDB libraries
  • 19-08-2008 Added links to the CDDF (CathDomainDescriptionFiles)
  • 22-05-2009 Ollie: Added links to Cathedral library file for v3.2 and v3.1.

CATH Releases

Version v3.4

Type Description Download (right-click and “Save as…”)
CathDomainPdb Library of chopped PDB files for representative CATH domains CathDomainPdb.S35.tgz (220 M)
CathCathedral library Library of domain secondary structure graphs for CATHEDRAL for representative CATH domains Class1-4.s35.cathedral.library (69 M)
CathHmm HMM library file for CATH domains hmmer.lib.gz (102 M)
CathHmm (+unclassified) HMM library file for CATH domains (including those that are waiting to be classified) hmmer.includingunclassifieddomains.lib.gz (131 M)
CathDomainDescriptionFile Full description of CATH domains CDDF (8.7 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (5.6 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (1.3 M)
Chains List of PDB chains in CATH CathChainList (8.5 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (22 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (22 M)
CathDomainList List of assigned CATH domains CathDomainList (9.1 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (192 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.ATOM (6.1 M)
CathDomainSeqs.S35.ATOM (1.6 M)
CathDomainSeqs.S60.ATOM (2.2 M)
CathDomainSeqs.S95.ATOM (2.9 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.COMBS (6.2 M)
CathDomainSeqs.S35.COMBS (1.6 M)
CathDomainSeqs.S60.COMBS (2.3 M)
CathDomainSeqs.S95.COMBS (3.0 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S100 (2.6 M)
CathDomainList.S35 (0.7 M)
CathDomainList.S60 (1.0 M)
CathDomainList.S95 (1.4 M)

Version v3.3

Type Description Download (right-click and “Save as…”)
CathDomainPdb Library of chopped PDB files for representative CATH domains CathDomainPdb.S35.tgz (220 M)
CathCathedral library Library of domain secondary structure graphs for CATHEDRAL for representative CATH domains Class1-4.s35.cathedral.library (69 M)
CathHmm HMM library file for CATH domains hmmer.lib.gz (102 M)
CathHmm (+unclassified) HMM library file for CATH domains (including those that are waiting to be classified) hmmer.includingunclassifieddomains.lib.gz (131 M)
CathDomainDescriptionFile Full description of CATH domains CDDF (8.7 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (5.6 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (1.3 M)
Chains List of PDB chains in CATH CathChainList (8.5 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (22 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (22 M)
CathDomainList List of assigned CATH domains CathDomainList (9.1 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (192 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.ATOM (6.1 M)
CathDomainSeqs.S35.ATOM (1.6 M)
CathDomainSeqs.S60.ATOM (2.2 M)
CathDomainSeqs.S95.ATOM (2.9 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.COMBS (6.2 M)
CathDomainSeqs.S35.COMBS (1.6 M)
CathDomainSeqs.S60.COMBS (2.3 M)
CathDomainSeqs.S95.COMBS (3.0 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S100 (2.6 M)
CathDomainList.S35 (0.7 M)
CathDomainList.S60 (1.0 M)
CathDomainList.S95 (1.4 M)

Version v3.2

Type Description Download (right-click and “Save as…”)
CathDomainPdb Library of chopped PDB files for representative CATH domains CathDomainPdb.S35.tgz (206 M)
CathDomainPdb.S60.tgz (291 M)
CathCathedral library Library of domain secondary structure graphs for CATHEDRAL for representative CATH domains Class1-4.s35.cathedral.library (63 M)
CathHmm HMM library file for CATH domains hmmer.lib.gz (91 M)
CathHmm (+unclassified) HMM library file for CATH domains (including those that are waiting to be classified) hmmer.includingunclassifieddomains.lib.gz (118 M)
CathDomainDescriptionFile Full description of CATH domains CDDF (7.9 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (5.11 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (1.09 M)
Chains List of PDB chains in CATH CathChainList (7.88 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (19.92 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (20.33 M)
CathDomainList List of assigned CATH domains CathDomainList (8.47 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (177.48 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.ATOM (5.55 M)
CathDomainSeqs.S35.ATOM (1.44 M)
CathDomainSeqs.S60.ATOM (2.03 M)
CathDomainSeqs.S95.ATOM (2.69 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.COMBS (5.70 M)
CathDomainSeqs.S35.COMBS (1.48 M)
CathDomainSeqs.S60.COMBS (2.09 M)
CathDomainSeqs.S95.COMBS (2.76 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S100 (2.31 M)
CathDomainList.S35 (658.02 K)
CathDomainList.S60 (911.06 K)
CathDomainList.S95 (1.22 M)

Version v3.1

Type Description Download (right-click and “Save as…”)
CathCathedral library Library of domain secondary structure graphs for CATHEDRAL for representative CATH domains Class1-4.s35.cathedral.library (63 M)
StructuralOverlap A 'structural overlap matrix' giving information for all the structural overlaps between different folds in CATH structural_overlap_matrix.dat
StructuralDiversity File of CATH superfamilies and number of structurally similar groups (SSGs) in those families. The number of SSG's are a measure of structural diversity. structural_diversity_matrix.dat
ArchitectureFunctionPopulation File giving functional information and population statistics for CATH architectures architecture_goterms.dat
CathDomainPdb Library of chopped PDB files for representative CATH domains CathDomainPdb.S35.tgz (183 M)
CathDomainPdb.S60.tgz (245 M)
CathHmm HMM library file for CATH domains hmmer.lib.gz (80 M)
CathHmm (+unclassified) HMM library file for CATH domains (including those that are waiting to be classified) hmmer.includingunclassifieddomains.lib.gz (87 M)
CathDomainDescriptionFile Full description of CATH domains CDDF (103 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (3.87 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (230.22 K)
Chains List of PDB chains in CATH CathChainList (6.21 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (16.31 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (16.62 M)
CathDomainList List of assigned CATH domains CathDomainList (6.96 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (171.91 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.ATOM (4.53 M)
CathDomainSeqs.S35.ATOM (1.27 M)
CathDomainSeqs.S60.ATOM (1.71 M)
CathDomainSeqs.S95.ATOM (2.25 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S100.COMBS (4.64 M)
CathDomainSeqs.S35.COMBS (1.30 M)
CathDomainSeqs.S60.COMBS (1.76 M)
CathDomainSeqs.S95.COMBS (2.30 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S100 (1.89 M)
CathDomainList.S35 (578.22 K)
CathDomainList.S60 (768.86 K)
CathDomainList.S95 (1.02 M)

Version v3.0

Type Description Download (right-click and “Save as…”)
CathDomainPdb Library of chopped PDB files for representative CATH domains CathDomainPdb.S35.tgz (183 M)
CathDomainPdb.S60.tgz (237 M)
CathHmm HMM library file for CATH domains hmmer.lib.gz (79 M)
CathDomainDescriptionFile Full description of CATH domains CDDF (91 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (3.52 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (138.45 K)
Chains List of PDB chains in CATH CathChainList (5.30 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (14.93 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (15.20 M)
CathDomainList List of assigned CATH domains CathDomainList (6.39 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (176.46 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S35.ATOM (1.28 M)
CathDomainSeqs.S60.ATOM (1.65 M)
CathDomainSeqs.S95.ATOM (2.12 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S35.COMBS (1.31 M)
CathDomainSeqs.S60.COMBS (1.69 M)
CathDomainSeqs.S95.COMBS (2.17 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S100 (1.77 M)
CathDomainList.S35 (581.69 K)
CathDomainList.S60 (743.07 K)
CathDomainList.S95 (966.06 K)

Version v2.6

Type Description Download (right-click and “Save as…”)
CathDomainDescriptionFile Full description of CATH domains CDDF (67 M)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (1.83 M)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (571.26 K)
Chains List of PDB chains in CATH CathChainList (1.01 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (11.66 M)
Domain Sequences (COMBS) FASTA sequence database for all CATH domains (based on COMBS sequence data) CathDomainSeqs.COMBS (11.83 M)
CathDomainList List of assigned CATH domains CathDomainList (4.03 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (119.82 K)
Representative Domain Sequences (ATOM) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S35.ATOM (981.27 K)
CathDomainSeqs.S95.ATOM (1.66 M)
Representative Domain Sequences (COMBS) FASTA sequence database for CATH domains (clustered at different levels of sequence identity) CathDomainSeqs.S35.COMBS (1.00 M)
CathDomainSeqs.S95.COMBS (1.69 M)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S35 (361.30 K)
CathDomainList.S95 (611.79 K)

Version v2.5

Type Description Download (right-click and “Save as…”)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (1.04 M)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (8.56 M)
CathDomainList List of assigned CATH domains CathDomainList (2.00 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (105.70 K)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S35 (187.16 K)
CathDomainList.S95 (349.04 K)

Version v2.4

Type Description Download (right-click and “Save as…”)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (824.58 K)
CathUnclassifiedList List of CATH domains that are waiting to be assigned CathUnclassifiedList (101.81 K)
Chains List of PDB chains in CATH CathChainList (368.83 K)
Domain Sequences (ATOM) FASTA sequence database for all CATH domains (based on ATOM records in PDB) CathDomainSeqs.ATOM (6.03 M)
CathDomainList List of assigned CATH domains CathDomainList (1.59 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (67.11 K)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S35 (152.30 K)

Version v2.0

Type Description Download (right-click and “Save as…”)
CathDomall Domain boundaries for each PDB Chain in “domall” format CathDomall (633.35 K)
Chains List of PDB chains in CATH CathChainList (308.35 K)
CathDomainList List of assigned CATH domains CathDomainList (1.27 M)
CathNames List of manually assigned names of CATH classification nodes CathNames (59.65 K)
Representatives List of CATH representative domains (representing clusters at different levels of sequence identity) CathDomainList.S35 (124.08 K)
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