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+ | {{tag>structure}} | ||
+ | ====== Class ======= | ||
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+ | This is the highest level of classification and is derived from the gross secondary structure | ||
+ | content. There are 4 classes defined in the CATH classification. | ||
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+ | - Mainly Alpha | ||
+ | - Mainly Beta | ||
+ | - Alpha Beta | ||
+ | - Few Secondary Structures. | ||
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+ | The classification of protein domains into these 4 classes has been achieved for 90% of | ||
+ | structures automatically, using an automated class assignment protocol. This classification protocol includes a number of criteria: | ||
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+ | * Percentage composition of secondary structures | ||
+ | * Percentage of secondary structures contacts | ||
+ | * Secondary structure alternation | ||
+ | * Percentage of parallel strands | ||
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+ | This is discussed in detail in the paper referenced below. | ||
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+ | ===== References ===== | ||
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+ | {{pubmed>long:8831787}} | ||
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