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glossary:class [2008/08/11 09:34]
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glossary:class [2008/08/11 09:34] (current)
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 +{{tag>structure}}
 +====== Class =======
 +
 +This is the highest level of classification and is derived from the gross secondary structure
 +content. There are 4 classes defined in the CATH classification.
 +
 +  -  Mainly Alpha
 +  -  Mainly Beta
 +  -  Alpha Beta
 +  -  Few Secondary Structures.
 +
 +The classification of protein domains into these 4 classes has been achieved for 90% of
 +structures automatically, using an automated class assignment protocol. This classification protocol includes a number of criteria:
 +
 +  * Percentage composition of secondary structures
 +  * Percentage of secondary structures contacts
 +  * Secondary structure alternation
 +  * Percentage of parallel strands
 +
 +This is discussed in detail in the paper referenced below.
 +
 +
 +===== References =====
 +
 +{{pubmed>long:8831787}}
 +
 +
 +
  
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