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glossary:beta_helix [2008/08/12 14:24]
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glossary:beta_helix [2008/09/17 09:31] (current)
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 +{{tag>beta}}
 +
 +
 +======  Beta Helix =======
 +
 +In this mainly beta fold, the polypeptide chain is wound into a large right-handed coil (or super helix).
 +There are two different types of beta helix, one with two [[glossary:beta_sheet | beta sheets]], and one with three beta
 +sheets. In our classification scheme we describe these as 2-solenoid and 3-solenoid beta
 +[[glossary:architecture | architectures]], respectively.
 +
 +__2-solenoid__
 +
 +This architecture comprises of two flat beta sheets
 +packed tightly against one another. It has a highly
 +distinctive and repetitive [[glossary:beta_strand | strand]] connectivity,
 +which distinguishes it from the two layer sandwich architecture.
 +The chain continually alternates between the two sheet layers whilst progressing in a
 +spiraling motion from one end of the structure to the other, hence the
 +term 'solenoid.' This could also be classified as a 2-layer beta sandwich but
 +its unusual lack of curvature and its unusual topology have led to it being
 +identified separately.
 +
 +__3-solenoid__
 +
 +Structures with this architecture comprise three beta sheets which
 +have a distinctive strand connectivity. The chain visits each sheet
 +in turn and is progressively wound around the principal axis in
 +the same direction.
 +
 +===== References =====
 +
 +{{pubmed>long:8081735}}
 +{{pubmed>long:8081738}}
 +
  
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