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glossary:ef_hand [2008/09/11 15:26] yan |
glossary:ef_hand [2008/09/17 08:51] (current) garner |
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+ | {{tag>alpha}} | ||
+ | ====== EF Hand ======= | ||
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+ | This is a helix-loop-helix, calcium-binding [[glossary:motif | motif]], in which two [[glossary:alpha_helix | helices]] pack | ||
+ | together at an angle of approximately 90 degrees, separated by a loop region, where | ||
+ | calcium binds. The 'EF' notation for the motif resulted from the structure of parvalbumin, in which the 'E' and 'F' helices were originally identified to form this calcium-binding motif. | ||
+ | The example shown is a human psoriasin (PDB code 1psr). | ||
+ | |||
+ | {{cath:feature>1psrA00}} | ||
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+ | ===== References ===== | ||
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+ | {{pubmed>long:8848832}} | ||
+ | {{pubmed>long:4700463}} | ||
+ | {{pubmed>long:2191555}} | ||