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glossary:ef_hand [2008/09/11 14:26]
yan
glossary:ef_hand [2008/09/17 07:51] (current)
garner
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 +{{tag>alpha}}
 +====== EF Hand =======
 +
 +This is a helix-loop-helix, calcium-binding  [[glossary:motif | motif]], in which two [[glossary:alpha_helix | helices]] pack
 +together at an angle of approximately 90 degrees, separated by a loop region, where
 +calcium binds. The 'EF' notation for the motif resulted from the structure of parvalbumin, in which the 'E' and 'F' helices were originally identified to form this calcium-binding motif.
 +The example shown is a human psoriasin (PDB code 1psr).
 +
 +{{cath:feature>1psrA00}}
 +
 +===== References =====
 +
 +{{pubmed>long:8848832}}
 +{{pubmed>long:4700463}}
 +{{pubmed>long:2191555}}
  
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